AFMC President & Symposium Chair Esin AKI-YALCIN
Prof. (PhD) Ankara University - Turkey
Organization Committee Chair of the AIMECS 2019 Ismail YALÇIN
Prof. (PhD) Ankara University - Turkey
Symposium Secretariat Sinan SENEM Phone :
Fax :
Click here to download the complete AIMECS 2019 programme.
| Sunday September 08, 2019 | |||||
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| 12:00-17:00 | Registration | ||||
| 17:00-19:00 | Welcome Ceremony | ||||
| Opening Session | |||||
| Session Chair: İsmail YALÇIN (Organization Committee Chair, Ankara, Turkey) | |||||
| Prof. Dr. Esin AKI-YALÇIN (President of The Asian Federation of Medisinal Chemistry) | |||||
| Dr. Mete HÜSEMOĞLU (Chairman of The Association of Turkish Research-Based Pharmaceutical Companies) | |||||
| Dr. Hakkı GÜRSÖZ (President of Turkish Medicines & Medicial Devices Agency) | |||||
| Prof. Dr. Hasan MANDAL (President of The Scientific & Technological Research Council of Turkey) | |||||
| Opening Lecture | |||||
| 19:00-19:45 | Toshi-Hiko KOBAYASHI (University of Tokyo, Japan) REGENERATIVE MEDICINE & EXAMPLES | ||||
| 19:45-21:30 | Welcome Party | ||||
| Monday September 09, 2019 | |||||
|---|---|---|---|---|---|
| Session 1: Recent Developments in Drug Discovery-I | |||||
| Session Chair: Dai-Shi SU (GlaxoSmithKline (GSK), Pennsylvania, USA) | |||||
| 09:00 | KS01 | Amiram GOLDBLUM (The Hebrew University of Jerusalem, Jerusalem, Israel) ITERATIVE STOCHASTIC ELIMINATION FOR MOLECULAR DISCOVERY | |||
| 09:35 | KS02 | Reuben Jih Ru HWU (National Tsing Hua University, Taiwan) NOVEL ANTI-VIRAL AGENTS WITH DIMERIC STRUCTURES | |||
| 10:10 | OP01 | Emmanuel MIKROS (National and Kapodistrian University of Athens, Greece) ANALYTICAL TOOLS ACCELERATING BIOACTIVE NATURAL PRODUCT DISCOVERY | |||
| 10:30-10:50 | Coffee Break | ||||
| Session 2: Recent Developments in Drug Discovery-II | |||||
| Session Chair: Minsoo SONG (New Drug Development Center, DGMIF, South Korea) | |||||
| 10:50 | KS03 | Anna TSANTILI (University of Athens, Greece) FRACTION LIPOPHILICITY INDEX (FLI). A WEIGHTED COMBINATION OF LOGP AND LOGD AS A DRUG-LIKE METRIC FOR IONIZABLE CHEMICAL ENTITIES | |||
| 11:25 | OP02 | Vedat EGILMEZ (Pharnaceutical Manufacturers Association of Turkey) NEW ROAD MAP FOR THE TURKISH PHARMA INDUSTRY: BIOPHARMACEUTICALS | |||
| 11:45 | OP03 | Vladimir A. PALYULIN (Lomonosov Moscow State University, Russia) AMPA RECEPTOR MODULATORS: DESIGN OF NEW SCAFFOLDS | |||
| 12:05 | OP04 | Karolina PAVIC (Turku Bioscience Centre, University of Turku, Turku, Finland) STRUCTURAL MECHANISM OF PP2A-B56 INHIBITION BY CIP2A | |||
| 12:25-14:25 | Lunch & Poster Session | ||||
| Session 3: Association of Research-Based Pharmaceutical Companies (AIFD) Session | |||||
| Session Chair: Ümit DERELI (General Secretary of the AIFD, Istanbul, Turkey) | |||||
| 14:25 | KS04 | Rana SANYAL (Department of Chemistry, Bogaziçi University, Istanbul, Turkey) TARGETED NANOMEDICINES AS CHEMOTHERAPY AGENTS | |||
| 15:00 | KS05 | Nesrin OZOREN (Molecular Biology and Genetics, Bogaziçi University, Istanbul, Turkey) FROM BASIC INNATE IMMUNITY TO NOVEL VACCINE TECHNOLOGY | |||
| 15:35 | OP05 | Mustafa Cem AÇIK (Pfizer Turkey General Manager, Istanbul, Turkey) PATIENS FIRST: HOW PATIENT CENTRICITY CAN HAVE A DIRECT ROLE IN THE FUTURE OF HEALTHCARE | |||
| 16:05-16:25 | Coffee Break | ||||
| Session 4:Advances in Medicinal Chemistry | |||||
| Session Chair: Reuben Jih Ru HWU (National Tsing Hua University, Taiwan) | |||||
| 16:25 | KS06 | Minsoo SONG (New Drug Development Center, DGMIF, South Korea) DEVELOPMENT OF TRIPLE-REUPTAKE INHIBITOR FOR ADHD USING MEDICINAL CHEMISTRY PLATFORM TECHNOLOGIES AT NEW DRUG DEVELOPMENT CENTER (NDDC), DGMIF | |||
| 17:00 | KS07 | Adam DAïCH (Université Le Havre Normandie, France) N,S-ACETAL SCAFFOLDS BASED ON CASCADE PROCESS INVOLVING IONIC SPECIES AND FUNCTIONALIZATION: NEW HITS AS FTASE INHIBITORS AND ANTIBACTERIAL AGENTS | |||
| 17:35 | OP06 | Kentaro TAKAYAMA (Tokyo University of Pharmacy And Life Sciences, Japan) IDENTIFICATION AND STRUCTURE-ACTIVITY RELATIONSHIP OF THE MINIMUM PEPTIDE STRUCTURE DERIVED FROM ENDOGENOUS MYOSTATIN INHIBITORY MOLECULES | |||
| 17:55 | OP07 | In Su KIM (Sungkyunkwan University, Suwon, South Korea) CATALYTIC C-H ALLYLATION: ACCESS TO BIOACTIVE SCAFFOLDS | |||
| 18:15 | OP08 | Maryam SAADAT (Tabriz University of Medical Sciences, Tabriz, Iran) SYNTHESIS AND CHARACTERIZATION OF TWO CATIONIC SURFACTANTS USED IN PHARMACEUTICAL APPLICATIONS | |||
| Tuesday September 10, 2019 | |||||
|---|---|---|---|---|---|
| Session 5: Recent Developments in Central Nervous System Drugs (ACS Session) | |||||
| Session Chair: Anna Katharina HIRSCH (Helmholtz Institute for Pharmaceutical Research Saarland, Germany) | |||||
| 09:00 | KS08 | Dai-Shi SU (GlaxoSmithKline (GSK), Pennsylvania, USA) SMALL MOLECULE ALLOSTERIC MODULATION OF LRRK2 | |||
| 09:35 | OP09 | Jong-Hyun PARK (Korea Institute of Science and Technology, South Korea) NEW REVERSIBLE MAO-B INHIBITOR CIRCUMVENTS THE SHORTCOMINGS OF IRREVERSIBLE INHIBITORS AND ALLEVIATE MEMORY IMPAIRMENT IN ALZHEIMER'S DISEASE MODEL | |||
| 09:55 | OP10 | Masayuki NASHIMOTO (Niigata University, Japan) DEVELOPMENT OF THERAPEUTIC HEPTAMER-TYPE sgRNAs AGAINST MULTIPLE MYELOMA | |||
| 10:15 | OP11 | Sofia DOMINGOS (University of Lisbon, Portugal) TOWARDS NOVEL PARKINSON'S DISEASE TREATMENTS: AN INNOVATIVE YEAST-BASED PLATFORM FOR THE DEVELOPMENT OF LRRK2 INHIBITORS | |||
| 10:35-10:55 | Coffee Break | ||||
| Session 6: Recent Developments in the Therapy of Infectious & Antiviral Diseases (EFMC Session) | |||||
| Session Chair: Koen AUGUSTYNS (University of Antwerp, Belgium) | |||||
| 10:55 | KS09 | Anna Katharina HIRSCH (Helmholtz Institute for Pharmaceutical Research Saarland, Germany) DISCOVERY OF THE FIRST ANTIBACTERIAL AGENT INHIBITING THE ENERGY-COUPLING FACTOR (efc) TRANSPORTERS BY STRUCTURE-BASED VIRTUAL SCREENING | |||
| 11:30 | KS10 | David WINKLER (Monash University, Melbourne, Australia) DESIGN OF ANTIFIBROTIC AGENTS AND MATERIALS FOR THERAPEUTIC AND MEDICAL DEVICE APPLICATION | |||
| 12:05 | OP12 | Vladimir SULIMOV (Lomonosov Moscow State University, Moscow, Russia) DEVELOPMENT OF DOCKING PROGRAMS FOR LOMONOSOV SUPERCOMPUTER | |||
| 12:25 | OP13 | Leni RITMALENI (Universitas Gadjah Mada, Indonesia) ANTIBACTERIAL ACTIVITY OF CURCUMIN ANALOGS, SOME DIBENZYLIDENE-CYCLOHEXANONE | |||
| 12:45-14:40 | Lunch & Poster Session | ||||
| 12:50-14:30 | AFMC General Assembly | ||||
| Session 7: Chemical Probes in Drug Discovery & Advances in Medicinal Chemistry | |||||
| Session Chair: Amiram GOLDBLUM (The Hebrew University of Jerusalem, Jerusalem, Israel) | |||||
| 14:40 | KS11 | Nir LONDON (The Weizmann Institute of Science, Israel) COVALENT INHIBITORS ON DEMAND - COMPUTATIONAL AND EMPIRICAL COVALENT LIGAND DISCOVERY | |||
| 15:15 | OP14 | Motomu KANAI (The University of Tokyo, Japan) CATALYTIC PHOTOOXYGENATION OF AMYLOID PROTEINS | |||
| 15:35 | OP15 | Andrey MARKOV (Siberian Branch of The Russian Academy Of Sciences, Russia) CYANO ENONE-BEARING TRITERPENOID SOLOXOLONE METHYL: MULTI-TARGET MODULATOR OF TUMOR GROWTH AND INFLAMMATION | |||
| 15:55 | OP16 | Hendris WONGSO (University Of Wollongong, Australia) DESIGN, SYNTHESIS AND BIOLOGICAL CHARACTERIZATION OF NOVEL TSPO-BINDING FLUORESCENT PROBES FOR IMAGING NEURODEGENERATIVE DISEASES | |||
| 16:15-16:35 | Coffee Break | ||||
| Session 8: Protein-Protein Interactions and Protein Target Dynamics for Drug Discovery | |||||
| Session Chair: Arry YANUAR (University of Indonesia, Depok, West Java, Indonesia) | |||||
| 16:35 | OP17 | Sun CHOI (Ewha Womans University, South Korea) COMPREHENSIVE MECHANISTIC STUDIES OF A TETRASPANIN ARGININE SENSOR FOR THE ELUCIDATION OF MODE OF ACTION AND INHIBITOR DISCOVERY | |||
| 16:55 | OP18 | Thomas EVANGELIDIS (The Czech Academy of Sciences, Czech Republic) PROTEIN-LIGAND BINDING AFFINITY PREDICTION VIA ARTIFICIAL INTELLIGENCE AND QUANTUM CHEMISTRY | |||
| 17:15 | OP19 | Daniela VALENSIN (University of Siena, Italy) STRUCTURAL ANALYSIS OF PROTEIN INTERACTIONS WITH MULTI TARGET DRUGS FOR THE TREATMENT OF NEURODEGENERATION | |||
| 17:35 | OP20 | Saltuk Mustafa EYRILMEZ (Institute of Organic Chemistry And Biochemistry, Czech Republic) ON THE PERFORMANCE OF SEMIEMPIRICAL QUANTUM MECHANICS-BASED SCORING FUNCTIONS FOR VIRTUAL SCREENING APPLICATIONS | |||
| 19:30 | Gala Dinner in the Cruise at the Bhosphorus | ||||
| Wedneday September 11, 2019 | |||||
|---|---|---|---|---|---|
| Session 9: Deep Learning & Miscellaneous Drug Targets | |||||
| Session Chair: David WINKLER (Monash University, Melbourne, Australia) | |||||
| 09:00 | KS12 | Arry YANUAR (University of Indonesia, Depok, West Java, Indonesia) THE USE OF DEEP LEARNING METHOD FOR CLASSIFICATION OF NEW PSYCHOACTIVE SUBSTANCE | |||
| 09:35 | OP21 | Nastaran HASHEMZADEH (Tabriz University of Medical Sciences, Tabriz, Iran) COMBINATION THERAPY OF METFORMIN AND ERLOTINIB USING MESOPOROUS SILICA MAGNETIC NANOPARTICLES IN 2D AND 3D CULTURED MCF-7 CELLS | |||
| 09:55 | OP22 | Jorge GRILO (University of Lisbon, Portugal) NEW OPPORTUNITIES FOR AN EVER-PRESENT THREAT: CLICK CHEMISTRY TOOLS TO UNRAVEL NEW DRUG TARGETS IN MALARIA | |||
| 10:15 | OP23 | Farnaz KHALESEH (Tabriz University of Medical Sciences, Iran) OPTIMIZATION AND CHARACTERIZATION OF AMIODARONE LOADED SOLID LIPID NANOPARTICLES BY DESIGN OF EXPERIMENT | |||
| 10:35-10:55 | Coffee Break | ||||
| Session 10: Computer Aided Drug Design Approaches - I | |||||
| Session Chair: Anna TSANTILI (University of Athens, Greece) | |||||
| 10:55 | OP24 | Supat JIRANUSORNKUL (Chiang Mai University, Thailand) INTEGRATIVE MOLECULAR MODELLING FOR NATURAL COSMECEUTICAL APPLICATION | |||
| 11:15 | OP25 | Simla OLGAC (Gazi University, Faculty of Pharmacy, Ankara, Turkey) VIRTUAL SCREENING TO DISCOVER DRUG CANDIDATES TARGETING PLATELET RECEPTORS | |||
| 11:35 | OP26 | Ozum OZTURK (Ankara University, Faculty of Pharmacy, Ankara, Turkey) MOLECULAR MODELING STUDIES OF BENZIMIDAZOLES AS CHOLINESTERASE INHIBITORS | |||
| 11:55 | OP27 | Anand GAURAV (UCSI University, Malaysia) IDENTIFICATION OF NOVEL PDE10A INHIBITORS USING PHARMACOPHORE-BASED VIRTUAL SCREENING AND MOLECULAR DOCKING METHODS | |||
| 12:15 - 13:30 | Lunch | ||||
| Session 11: Computer Aided Drug Design Approaches - II | |||||
| Session Chair: Anna TSANTILI (University of Athens, Greece) | |||||
| 13:30 | OP28 | Asli TURE (Marmara University, Faculty of Pharmacy, Istanbul, Turkey) NOVEL MODIFIED FLUOROQUINOLONE DERIVATIVES AS POTENTIAL ANTIBACTERIAL AND ANTI-TUBERCULOSIS AGENTS: DESIGN, SYNTHESIS AND MOLECULAR MODELING STUDIES | |||
| 13:50 | OP29 | Tugce OZYAZICI (Yeditepe University, Faculty of Pharmacy, Istanbul, Turkey) SYNTHESIS AND BIOLOGICAL ACTIVITY STUDIES OF NEW 1,3,4-OXADIAZOLE DERIVATIVES | |||
| 14:10 | OP30 | Efe Dogukan DINCEL (Istanbul University, Istanbul, Turkey) SYNTHESIS AND COMPUTER-AIDED DRUG DESIGN STUDIES OF NOVEL 1,2,4-TRIAZOLE-3-THIONE DERIVATIVES AS POTENT AND TARGET-ORIENTED THERAPEUTIC AGENTS | |||
| 14:30-14:50 | Closing Session | ||||
KP: Keynote Presentation
OP: Oral Presentation
Asian Federation for Medicinal Chemistry
European Federation for Medicinal Chemistry
American Chemical Society
Pharmaceutical Manufacturers Association of Turkey
Association of Research-Based Pharmaceutical Companies
