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AFMC President & Symposium Chair Esin AKI-YALCIN
Prof. (PhD)
Ankara University - Turkey


Organization Committee Chair of the AIMECS 2019 Ismail YALÇIN
Prof. (PhD)
Ankara University - Turkey


Symposium Secretariat Sinan SENEM Phone :
+90 312 419 0 998
Fax :
+90 312 419 1 888
info@aimecs2019.org



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Programme

Click here to download the complete AIMECS 2019 programme.

Sunday September 08, 2019
12:00-17:00 Registration
17:00-19:00 Welcome Ceremony
Opening Session
Session Chair: İsmail YALÇIN (Organization Committee Chair, Ankara, Turkey)
Prof. Dr. Esin AKI-YALÇIN (President of The Asian Federation of Medisinal Chemistry)
Dr. Mete HÜSEMOĞLU (Chairman of The Association of Turkish Research-Based Pharmaceutical Companies)
Dr. Hakkı GÜRSÖZ (President of Turkish Medicines & Medicial Devices Agency)
Prof. Dr. Hasan MANDAL (President of The Scientific & Technological Research Council of Turkey)
Opening Lecture
19:00-19:45 Toshi-Hiko KOBAYASHI (University of Tokyo, Japan) REGENERATIVE MEDICINE & EXAMPLES
19:45-21:30 Welcome Party
Monday September 09, 2019
Session 1: Recent Developments in Drug Discovery-I
Session Chair: Dai-Shi SU (GlaxoSmithKline (GSK), Pennsylvania, USA)
09:00 KS01 Amiram GOLDBLUM (The Hebrew University of Jerusalem, Jerusalem, Israel) ITERATIVE STOCHASTIC ELIMINATION FOR MOLECULAR DISCOVERY
09:35 KS02 Reuben Jih Ru HWU (National Tsing Hua University, Taiwan) NOVEL ANTI-VIRAL AGENTS WITH DIMERIC STRUCTURES
10:10 OP01 Emmanuel MIKROS (National and Kapodistrian University of Athens, Greece) ANALYTICAL TOOLS ACCELERATING BIOACTIVE NATURAL PRODUCT DISCOVERY
10:30-10:50 Coffee Break
Session 2: Recent Developments in Drug Discovery-II
Session Chair: Minsoo SONG (New Drug Development Center, DGMIF, South Korea)
10:50 KS03 Anna TSANTILI (University of Athens, Greece) FRACTION LIPOPHILICITY INDEX (FLI). A WEIGHTED COMBINATION OF LOGP AND LOGD AS A DRUG-LIKE METRIC FOR IONIZABLE CHEMICAL ENTITIES
11:25 OP02 Vedat EGILMEZ (Pharnaceutical Manufacturers Association of Turkey) NEW ROAD MAP FOR THE TURKISH PHARMA INDUSTRY: BIOPHARMACEUTICALS
11:45 OP03 Vladimir A. PALYULIN (Lomonosov Moscow State University, Russia) AMPA RECEPTOR MODULATORS: DESIGN OF NEW SCAFFOLDS
12:05 OP04 Karolina PAVIC (Turku Bioscience Centre, University of Turku, Turku, Finland) STRUCTURAL MECHANISM OF PP2A-B56 INHIBITION BY CIP2A
12:25-14:25 Lunch & Poster Session
Session 3: Association of Research-Based Pharmaceutical Companies (AIFD) Session
Session Chair: Ümit DERELI (General Secretary of the AIFD, Istanbul, Turkey)
14:25 KS04 Rana SANYAL (Department of Chemistry, Bogaziçi University, Istanbul, Turkey) TARGETED NANOMEDICINES AS CHEMOTHERAPY AGENTS
15:00 KS05 Nesrin OZOREN (Molecular Biology and Genetics, Bogaziçi University, Istanbul, Turkey) FROM BASIC INNATE IMMUNITY TO NOVEL VACCINE TECHNOLOGY
15:35 OP05 Mustafa Cem AÇIK (Pfizer Turkey General Manager, Istanbul, Turkey) PATIENS FIRST: HOW PATIENT CENTRICITY CAN HAVE A DIRECT ROLE IN THE FUTURE OF HEALTHCARE
16:05-16:25 Coffee Break
Session 4:Advances in Medicinal Chemistry
Session Chair: Reuben Jih Ru HWU (National Tsing Hua University, Taiwan)
16:25 KS06 Minsoo SONG (New Drug Development Center, DGMIF, South Korea) DEVELOPMENT OF TRIPLE-REUPTAKE INHIBITOR FOR ADHD USING MEDICINAL CHEMISTRY PLATFORM TECHNOLOGIES AT NEW DRUG DEVELOPMENT CENTER (NDDC), DGMIF
17:00 KS07 Adam DAïCH (Université Le Havre Normandie, France) N,S-ACETAL SCAFFOLDS BASED ON CASCADE PROCESS INVOLVING IONIC SPECIES AND FUNCTIONALIZATION: NEW HITS AS FTASE INHIBITORS AND ANTIBACTERIAL AGENTS
17:35 OP06 Kentaro TAKAYAMA (Tokyo University of Pharmacy And Life Sciences, Japan) IDENTIFICATION AND STRUCTURE-ACTIVITY RELATIONSHIP OF THE MINIMUM PEPTIDE STRUCTURE DERIVED FROM ENDOGENOUS MYOSTATIN INHIBITORY MOLECULES
17:55 OP07 In Su KIM (Sungkyunkwan University, Suwon, South Korea) CATALYTIC C-H ALLYLATION: ACCESS TO BIOACTIVE SCAFFOLDS
18:15 OP08 Maryam SAADAT (Tabriz University of Medical Sciences, Tabriz, Iran) SYNTHESIS AND CHARACTERIZATION OF TWO CATIONIC SURFACTANTS USED IN PHARMACEUTICAL APPLICATIONS
Tuesday September 10, 2019
Session 5: Recent Developments in Central Nervous System Drugs (ACS Session)
Session Chair: Anna Katharina HIRSCH (Helmholtz Institute for Pharmaceutical Research Saarland, Germany)
09:00 KS08 Dai-Shi SU (GlaxoSmithKline (GSK), Pennsylvania, USA) SMALL MOLECULE ALLOSTERIC MODULATION OF LRRK2
09:35 OP09 Jong-Hyun PARK (Korea Institute of Science and Technology, South Korea) NEW REVERSIBLE MAO-B INHIBITOR CIRCUMVENTS THE SHORTCOMINGS OF IRREVERSIBLE INHIBITORS AND ALLEVIATE MEMORY IMPAIRMENT IN ALZHEIMER'S DISEASE MODEL
09:55 OP10 Masayuki NASHIMOTO (Niigata University, Japan) DEVELOPMENT OF THERAPEUTIC HEPTAMER-TYPE sgRNAs AGAINST MULTIPLE MYELOMA
10:15 OP11 Sofia DOMINGOS (University of Lisbon, Portugal) TOWARDS NOVEL PARKINSON'S DISEASE TREATMENTS: AN INNOVATIVE YEAST-BASED PLATFORM FOR THE DEVELOPMENT OF LRRK2 INHIBITORS
10:35-10:55 Coffee Break
Session 6: Recent Developments in the Therapy of Infectious & Antiviral Diseases (EFMC Session)
Session Chair: Koen AUGUSTYNS (University of Antwerp, Belgium)
10:55 KS09 Anna Katharina HIRSCH (Helmholtz Institute for Pharmaceutical Research Saarland, Germany) DISCOVERY OF THE FIRST ANTIBACTERIAL AGENT INHIBITING THE ENERGY-COUPLING FACTOR (efc) TRANSPORTERS BY STRUCTURE-BASED VIRTUAL SCREENING
11:30 KS10 David WINKLER (Monash University, Melbourne, Australia) DESIGN OF ANTIFIBROTIC AGENTS AND MATERIALS FOR THERAPEUTIC AND MEDICAL DEVICE APPLICATION
12:05 OP12 Vladimir SULIMOV (Lomonosov Moscow State University, Moscow, Russia) DEVELOPMENT OF DOCKING PROGRAMS FOR LOMONOSOV SUPERCOMPUTER
12:25 OP13 Leni RITMALENI (Universitas Gadjah Mada, Indonesia) ANTIBACTERIAL ACTIVITY OF CURCUMIN ANALOGS, SOME DIBENZYLIDENE-CYCLOHEXANONE
12:45-14:40 Lunch & Poster Session
12:50-14:30 AFMC General Assembly
Session 7: Chemical Probes in Drug Discovery & Advances in Medicinal Chemistry
Session Chair: Amiram GOLDBLUM (The Hebrew University of Jerusalem, Jerusalem, Israel)
14:40 KS11 Nir LONDON (The Weizmann Institute of Science, Israel) COVALENT INHIBITORS ON DEMAND - COMPUTATIONAL AND EMPIRICAL COVALENT LIGAND DISCOVERY
15:15 OP14 Motomu KANAI (The University of Tokyo, Japan) CATALYTIC PHOTOOXYGENATION OF AMYLOID PROTEINS
15:35 OP15 Andrey MARKOV (Siberian Branch of The Russian Academy Of Sciences, Russia) CYANO ENONE-BEARING TRITERPENOID SOLOXOLONE METHYL: MULTI-TARGET MODULATOR OF TUMOR GROWTH AND INFLAMMATION
15:55 OP16 Hendris WONGSO (University Of Wollongong, Australia) DESIGN, SYNTHESIS AND BIOLOGICAL CHARACTERIZATION OF NOVEL TSPO-BINDING FLUORESCENT PROBES FOR IMAGING NEURODEGENERATIVE DISEASES
16:15-16:35 Coffee Break
Session 8: Protein-Protein Interactions and Protein Target Dynamics for Drug Discovery
Session Chair: Arry YANUAR (University of Indonesia, Depok, West Java, Indonesia)
16:35 OP17 Sun CHOI (Ewha Womans University, South Korea) COMPREHENSIVE MECHANISTIC STUDIES OF A TETRASPANIN ARGININE SENSOR FOR THE ELUCIDATION OF MODE OF ACTION AND INHIBITOR DISCOVERY
16:55 OP18 Thomas EVANGELIDIS (The Czech Academy of Sciences, Czech Republic) PROTEIN-LIGAND BINDING AFFINITY PREDICTION VIA ARTIFICIAL INTELLIGENCE AND QUANTUM CHEMISTRY
17:15 OP19 Daniela VALENSIN (University of Siena, Italy) STRUCTURAL ANALYSIS OF PROTEIN INTERACTIONS WITH MULTI TARGET DRUGS FOR THE TREATMENT OF NEURODEGENERATION
17:35 OP20 Saltuk Mustafa EYRILMEZ (Institute of Organic Chemistry And Biochemistry, Czech Republic) ON THE PERFORMANCE OF SEMIEMPIRICAL QUANTUM MECHANICS-BASED SCORING FUNCTIONS FOR VIRTUAL SCREENING APPLICATIONS
19:30 Gala Dinner in the Cruise at the Bhosphorus
Wedneday September 11, 2019
Session 9: Deep Learning & Miscellaneous Drug Targets
Session Chair: David WINKLER (Monash University, Melbourne, Australia)
09:00 KS12 Arry YANUAR (University of Indonesia, Depok, West Java, Indonesia) THE USE OF DEEP LEARNING METHOD FOR CLASSIFICATION OF NEW PSYCHOACTIVE SUBSTANCE
09:35 OP21 Nastaran HASHEMZADEH (Tabriz University of Medical Sciences, Tabriz, Iran) COMBINATION THERAPY OF METFORMIN AND ERLOTINIB USING MESOPOROUS SILICA MAGNETIC NANOPARTICLES IN 2D AND 3D CULTURED MCF-7 CELLS
09:55 OP22 Jorge GRILO (University of Lisbon, Portugal) NEW OPPORTUNITIES FOR AN EVER-PRESENT THREAT: CLICK CHEMISTRY TOOLS TO UNRAVEL NEW DRUG TARGETS IN MALARIA
10:15 OP23 Farnaz KHALESEH (Tabriz University of Medical Sciences, Iran) OPTIMIZATION AND CHARACTERIZATION OF AMIODARONE LOADED SOLID LIPID NANOPARTICLES BY DESIGN OF EXPERIMENT
10:35-10:55 Coffee Break
Session 10: Computer Aided Drug Design Approaches - I
Session Chair: Anna TSANTILI (University of Athens, Greece)
10:55 OP24 Supat JIRANUSORNKUL (Chiang Mai University, Thailand) INTEGRATIVE MOLECULAR MODELLING FOR NATURAL COSMECEUTICAL APPLICATION
11:15 OP25 Simla OLGAC (Gazi University, Faculty of Pharmacy, Ankara, Turkey) VIRTUAL SCREENING TO DISCOVER DRUG CANDIDATES TARGETING PLATELET RECEPTORS
11:35 OP26 Ozum OZTURK (Ankara University, Faculty of Pharmacy, Ankara, Turkey) MOLECULAR MODELING STUDIES OF BENZIMIDAZOLES AS CHOLINESTERASE INHIBITORS
11:55 OP27 Anand GAURAV (UCSI University, Malaysia) IDENTIFICATION OF NOVEL PDE10A INHIBITORS USING PHARMACOPHORE-BASED VIRTUAL SCREENING AND MOLECULAR DOCKING METHODS
12:15 - 13:30 Lunch
Session 11: Computer Aided Drug Design Approaches - II
Session Chair: Anna TSANTILI (University of Athens, Greece)
13:30 OP28 Asli TURE (Marmara University, Faculty of Pharmacy, Istanbul, Turkey) NOVEL MODIFIED FLUOROQUINOLONE DERIVATIVES AS POTENTIAL ANTIBACTERIAL AND ANTI-TUBERCULOSIS AGENTS: DESIGN, SYNTHESIS AND MOLECULAR MODELING STUDIES
13:50 OP29 Tugce OZYAZICI (Yeditepe University, Faculty of Pharmacy, Istanbul, Turkey) SYNTHESIS AND BIOLOGICAL ACTIVITY STUDIES OF NEW 1,3,4-OXADIAZOLE DERIVATIVES
14:10 OP30 Efe Dogukan DINCEL (Istanbul University, Istanbul, Turkey) SYNTHESIS AND COMPUTER-AIDED DRUG DESIGN STUDIES OF NOVEL 1,2,4-TRIAZOLE-3-THIONE DERIVATIVES AS POTENT AND TARGET-ORIENTED THERAPEUTIC AGENTS
14:30-14:50 Closing Session

KP: Keynote Presentation
OP: Oral Presentation

ORGANISED BY

  • Asian Federation for Medicinal Chemistry

SUPPORTED BY

  • European Federation for Medicinal Chemistry

  • American Chemical Society

  • Pharmaceutical Manufacturers Association of Turkey

  • Association of Research-Based Pharmaceutical Companies

EXHIBITORS


MEDIA PARTNERS